Effects of Growth Hormone and Nutritional Therapy in Boys with Constitutional Growth Delay: A Randomized Controlled Trial
نویسندگان
چکیده
منابع مشابه
Treatment of constitutional delay of growth and puberty with oxandrolone compared with growth hormone.
The effects of oxandrolone or biosynthetic human growth hormone (r-hGH) on the growth of 26 boys with constitutional delay of growth and puberty were studied. Both regimens increased growth rate twofold, oxandrolone to a greater extent than r-hGH. We conclude that oxandrolone is a more effective method of increasing growth rate in such children.
متن کاملTreatment of constitutional growth delay in prepubertal boys with a prolonged course of low dose oxandrolone.
Forty six prepubertal boys who had constitutional growth delay were treated with oxandrolone. Mean age at the onset of treatment was 11.9 years (range 9.0-14.0) and bone age delay was 1.9 'years'. The dose of oxandrolone used was a mean of 0.05 mg/kg (range 0.03-0.18) for a mean of 0.9 years (range 0.2-3.6). Height velocity increased from a mean (SD) before treatment of 4.0 (1.0) to 7.5 (1.2) c...
متن کاملEvaluation of near final height in boys with constitutional delay in growth and puberty
BACKGROUND This study was conducted to find out whether boys with constitutional delay in growth and puberty (CDGP) could attain their target height and predicted adult height (PAH) in adulthood or not. METHODS After measuring the height, weight, pubertal stage, parental height and bone age data of the patients at their first presentation were extracted from the files and their height and wei...
متن کاملThe effects of growth hormone and/or testosterone in healthy elderly men: a randomized controlled trial.
CONTEXT Declines in GH and testosterone (Te) secretion may contribute to the detrimental aging changes of elderly men. OBJECTIVE To assess the effects of near-physiological GH with/without Te administration on lean body mass, total body fat, midthigh muscle cross-section area, muscle strength, aerobic capacity, condition-specific quality of life (Age-Related Hormone Deficiency-Dependent Quali...
متن کاملEstrogen receptor α polymorphism in boys with constitutional delay of growth and puberty
PURPOSE There were a lot of reports regarding associations of polymorphisms in the estrogen receptor α (ESR1). with many disorders. But, those with constitutional delay of growth and puberty (CDGP) are not known. Our aim is to find out any association between CDGP and ESR1. METHODS In a total of 27 subjects, we compared 7 CDGP patients with 20 healthy controls with their heights and sexual ma...
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ژورنال
عنوان ژورنال: The Journal of Pediatrics
سال: 2011
ISSN: 0022-3476
DOI: 10.1016/j.jpeds.2010.09.006